Research
Our team is actively involved in clinical research, primarily in the field of acute stroke management:
Local investigator-initiated projects
Multicentre investigator-initiated studies from other Canadian and international researchers
Multicentre industry-initiated studies
We generate approximately 20 publications annually (collective H-index 78)
Current projects lead by the CHUM Neurovascular Health Program
EASI-TOC (Endovascular Acute Stroke Intervention - Tandem OCclusion)
Multicentre randomised controlled trial of acute carotid stenting during thrombectomy in patients with tandem occlusion
Principal investigator: Dr Alexandre POPPE
BASiS-LVO (Biomarkers in Acute Stroke Study - Large Vessel Occlusion)
Study of plasmatic biomarkers of cerebrovascular disease in patients with suspected acute stroke , supported by Heart and Stroke Canada
Principal Investigator: Dr Laura GIOIA
MONSTER (MOntreal Neurovascular and STroke Repository)
Electronic medical record repository reporting on our neurovascular clinical activity (neurovascular emergencies, thrombolysis, thrombectomy, hospitalisations, outpatient clinic, etc.) to allow for quality assurance
Supervisor: Dr Christian STAPF
MORPHEUS
Research program studying procedural sedation, patient and operator comfort during thrombectomy.
Principal Investigator: Dr Grégory JACQUIN
COMPARE
Multicentre, international, retrospective study comparing stroke patients selected by MRI versus CT-CTA for thrombectomy.
Principal Investigators: Dr Alexandre POPPE, Dr Célina DUCROUX (Fellow)
LOCOMOTIVE
Principal Investigators: Dr Celine Odier
COVID-19 and Stroke
Single-centre prospective cohort study examining the characteristics, management and prognosis of acute stroke patients treated at CHUM during the COVID-19 pandemic. Publications
Principal Investigator: Dr Alexandre POPPE, Dr Joel NEVES BRIARD (Neurology resident)
Multicentre Studies
Ongoing: OPTIMISE, ENRICH-AF, FASTEST, OCEANIC-Stroke, EASI-TOC
Upcoming: AcT-GLOBAL, FASTEST, ACTION, ASPIRING, AcT-42
Completed: AcT, AXIOMATIC-SSP, ESCAPE, ESCAPE-NA1, ESCAPE-NEXT, NASPAF-ICH, DATAS-II, NAVIGATE ESUS, RE-SPECT ESUS, POINT, IMS-III, IRIS, CLOTBUST-ER, SPOTLIGHT, INTERSeCT, C-VASC, SECRET, CoVASC-ICH
Visiting Professors